4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid

4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid - Names and Identifiers

Name	4-(tert-butoxycarbonyl)benzoic acid
Synonyms	tert-Butyl terephthalate mono-(tert-Butyl) terephthalate tert-Butyl hydrogen terephthalate 4-(TERT-BUTOXYCARBONYL)BENZOIC ACID 4-(tert-butoxycarbonyl)benzoic acid 4-(tert-Butoxycarbonyl)benzoic acid TEREPHALIC ACID MONO TERT-BUTYL ESTER 4-[(2-methylpropan-2-yl)oxycarbonyl]benzoic Acid 4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid 1,4-Benzenedicarboxylic acid, mono(1,1-dimethylethyl) ester 4-(tert-Butoxycarbonyl)benzoic acid, tert-Butyl 4-carboxybenzoate
CAS	20576-82-3
InChI	InChI=1/C12H14O4/c1-12(2,3)16-11(15)9-6-4-8(5-7-9)10(13)14/h4-7H,1-3H3,(H,13,14)

4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid - Physico-chemical Properties

Molecular Formula	C12H14O4
Molar Mass	222.24
Density	1.173g/cm³
Melting Point	209-212(dec.)
Boling Point	351.8°C at 760 mmHg
Flash Point	132.8°C
Solubility	DMSO (Slightly), Ethyl Acetate (Slightly). Methanol (Slightly)
Vapor Presure	1.49E-05mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.533

4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

4-[(2-methylpropan-2-yl)oxy-oxomethyl]benzoic acid - Introduction

4-(tert-butoxycarbonyl)benzoic acid is an organic compound with the chemical formula C12H16O4. It has the following properties:

1. Appearance: It is a colorless to light yellow crystalline solid.
2. Melting point: Its melting point range is 82-86 degrees Celsius.
3. Solubility: It is easily soluble in organic solvents, such as ethanol, dimethylformamide and dichloromethane.
4. Stability: It is stable at room temperature, but may decompose at high temperature.

The main use of 4-(tert-butoxycarbonyl)benzoic acid is as an important compound in organic synthesis, which can be used in the synthesis of drugs, dyes, fragrances and coatings. It is commonly used as an esterifying agent, acylating agent and acylating agent.

The method for preparing 4-(tert-butoxycarbonyl)benzoic acid can be obtained by reacting benzoic acid with tert-butanol. The specific preparation method is as follows:
1. Benzoic acid and tert-butyl alcohol were mixed in a molar ratio of 1:1.2.
2. Slowly drop 0.5 moles of sulfuric acid or dimethyl sulfate as a catalyst at low temperature.
3. During the reaction, keep the reaction temperature at 0-5 degrees Celsius and stir well.
4. After completion of the reaction, the reaction mass was filtered and washed with cold ether.
5. Finally, the product obtained by washing is dried to obtain 4-(tert-butoxycarbonyl)benzoic acid.

Regarding safety information, 4-(tert-butoxycarbonyl)benzoic acid is a chemical, please note the following safety precautions:
1. Use should wear appropriate protective gloves, protective glasses and protective masks and other personal protective equipment.
2. Avoid skin contact and inhalation of powder. In case of accidental contact, rinse immediately with plenty of water.
3. Storage should avoid contact with oxidants and strong acids to avoid dangerous reactions.
4. If ingested by mistake or other accidents occur, seek medical attention immediately and show the safety data sheet to the doctor.

Last Update：2024-04-09 21:00:56